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Phenylketonuria (PKU) is a condition where your body can't break down an amino acid called phenylalanine. Know how to recognize phenylketonuria .Acta Paediatr. 2002;91(8):905-9. Homocysteine and other vascular risk factors in patients with phenylketonuria on a diet. Schulpis KH(1), Karikas GA, .Based on Input from Adults with PKU of all Ages and Situations PKU, both diet for lifers and returning to dieters, that can help you with your return.Most experts recommend that a phenylalanine-restricted diet should be life-long in persons with classical PKU. Classical PKU refers to persons with 2 severe .The current AA-based low-phe diet the current PKU diet from synthetic.